BDBM50481786 CHEMBL598504

SMILES CC[C@@H](N(CC)[C@@H](C)c1ccc(cc1)C(F)(F)F)c1ccc(nc1)C(F)(F)F

InChI Key InChIKey=DCMCSHAQMPMXLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50481786   

TargetPresenilin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50481786(CHEMBL598504)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant APP assessed as amyloid beta40 formation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50481786(CHEMBL598504)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gamma-secretase in human SHSY5Y cells expressing human recombinant APP assessed as amyloid beta42 formation by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed