BDBM50481802 CHEBI:67727::Furospongolide

SMILES C\C(CCCC1=CC(=O)OC1)=C/CC\C(C)=C\CCc1ccoc1

InChI Key InChIKey=WCHKEOQZUQGPSS-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50481802   

LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells after 16 hrs by pTK-HRE3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells after 16 hrs by pTK-HRE3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human PC3 cells after 16 hrs by pTK-HRE3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
LigandPNGBDBM50481802(CHEBI:67727 | Furospongolide)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 1,10-phenanthroline-induced HIF1 activation in human PC3 cells after 16 hrs by pTK-HRE3-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed