BDBM50481837 CHEMBL1077757

SMILES NS(=O)(=O)c1ccc(NC(=O)C2CC2C(=O)N2CCCc3cc(Cl)cc(Cl)c23)c(Cl)c1

InChI Key InChIKey=MXVZQFQXUZRZIR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50481837   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50481837(CHEMBL1077757)
Affinity DataIC50: 99nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant in human MT4 cells after 72 hrs by spread assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50481837(CHEMBL1077757)
Affinity DataIC50: 99nMAssay Description:Inhibition of HIV1 reverse transcriptase Y181C mutant in human MT4 cells after 72 hrs by spread assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50481837(CHEMBL1077757)
Affinity DataIC50: 210nMAssay Description:Inhibition of HIV1 reverse transcriptase expressed in human MT4 cells after 72 hrs by spread assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Merck Research Laboratory

Curated by ChEMBL
LigandPNGBDBM50481837(CHEMBL1077757)
Affinity DataIC50: 210nMAssay Description:Inhibition of HIV1 reverse transcriptase expressed in human MT4 cells after 72 hrs by spread assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed