BDBM50481893 CHEMBL1080015

SMILES CC(C)(Oc1ccc(cc1)C(\N=N\c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O)c1ccc(Cl)cc1)C(O)=O

InChI Key InChIKey=ZYVJLSOPEYAJSE-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481893   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481893(CHEMBL1080015)
Affinity DataIC50: 1.70E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481893(CHEMBL1080015)
Affinity DataIC50: 3.73E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta40 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481893(CHEMBL1080015)
Affinity DataEC50:  4.76E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as increase in amyloid beta38 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed