BDBM50481894 CHEMBL1079649

SMILES CN(C)c1ccc(cc1)\N=N\c1ccc(cc1)S(=O)(=O)n1c2ccccc2c2ccc(OCC(O)=O)cc12

InChI Key InChIKey=RKRSTYBMLMQCOQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481894   

TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481894(CHEMBL1079649)
Affinity DataEC50:  7.60E+3nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as increase in amyloid beta38 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481894(CHEMBL1079649)
Affinity DataIC50: 9.00E+3nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta42 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Technische Universit£T Darmstadt

Curated by ChEMBL
LigandPNGBDBM50481894(CHEMBL1079649)
Affinity DataIC50: 8.00E+4nMAssay Description:Modulation of gamma-secretase in human H4 cells assessed as inhibition of in amyloid beta40 production by LPECL assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMed