BDBM50482671 CHEMBL1224149

SMILES COc1cc(ccc1-n1cnc(C)c1)[C@H](O)C1CNC(=N)N([C@@H](C)c2ccc(F)cc2)C1=O

InChI Key InChIKey=YNUVMEAHUNFWMQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50482671   

TargetPresenilin-1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50482671(CHEMBL1224149)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of gamma secretase-mediated amyloid beta42 production in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed