BDBM50482821 CHEMBL1258587

SMILES Cc1cc(cc(C)c1Oc1nc(NC2CCN(CC2)c2cccc(c2)S(N)(=O)=O)ncc1Br)C#N

InChI Key InChIKey=LOSVSQZYWMNMOM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50482821   

TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482821(CHEMBL1258587)
Affinity DataIC50: 19nMAssay Description:Inhibition of HIV1 recombinant wild type reverse transcriptase by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase protein(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482821(CHEMBL1258587)
Affinity DataIC50: 72nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase K103N/Y181C double mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Roche R&D Center China

Curated by ChEMBL
LigandPNGBDBM50482821(CHEMBL1258587)
Affinity DataIC50: 105nMAssay Description:Inhibition of HIV1 recombinant reverse transcriptase Y188L mutant by SPA heteropolymeric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed