BDBM50483060 CHEMBL1277046::acs.jmedchem.1c00409_ST.374

SMILES OC(=O)c1ccc(\C=C2/C(=O)N(N=C2c2ccccc2)c2ccc(cc2)C#N)cc1

InChI Key InChIKey=LILSTRSJSINJSR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50483060   

TargetReplicase polyprotein 1ab(SARS-CoV)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50483060(CHEMBL1277046 | acs.jmedchem.1c00409_ST.374)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of SARS coronavirus 3C-like protease by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetGenome polyprotein(Coxsackievirus B3 (strain Nancy))
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50483060(CHEMBL1277046 | acs.jmedchem.1c00409_ST.374)
Affinity DataIC50: 2.08E+4nMAssay Description:Inhibition of coxsackievirus B3 3C protease by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
Academia Sinica

Curated by ChEMBL
LigandPNGBDBM50483060(CHEMBL1277046 | acs.jmedchem.1c00409_ST.374)
Affinity DataIC50: 5.50E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed