BDBM50483927 CHEMBL3183531

SMILES CCOC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1

InChI Key InChIKey=WBKCKEHGXNWYMO-UHFFFAOYSA-N

Data  17 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50483927   

TargetLysine-specific demethylase 5B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 9.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 7.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 5.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHistone lysine demethylase PHF8(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 4.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6A(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 6.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 5C(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetMethylcytosine dioxygenase TET1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataEC50:  1.60E+4nMAssay Description:Inhibition of tetracyclin/Dox-inducible N-terminal 3xFLAG/C-terminal GFP tagged human TET1 catalytic domain (1481 to 2136 residues) expressed in huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4C(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 5.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 4B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 3.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 7.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 3B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 3A(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 8.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 2B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetLysine-specific demethylase 6B(Human)
GlaxoSmithKline R&D

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of JMJD3 (unknown origin) by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
EpiTherapeutics Aps

Curated by ChEMBL
LigandPNGBDBM50483927(CHEMBL3183531)
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of KDM5B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed