BDBM50488814 CHEMBL2295942

SMILES CC(C)n1cnc2c(Nc3cccc(c3)-c3cncnc3)nc(Cl)nc12

InChI Key InChIKey=SFIQNGXRRVFNJS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50488814   

LigandPNGBDBM50488814(CHEMBL2295942)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Sus scrofa (pig) glycogen synthase kinase 3alpha/beta isolated from brain using YRRAAVPPSPSLSRHSSPHQpSEDEEE and [gamma33P]ATP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488814(CHEMBL2295942)
Affinity DataIC50: 380nMAssay Description:Inhibition of Sus scrofa (pig) casein kinase 1delta/epsilon isolated from brain using RRKHAAIGpSAYSITA and [gamma33P]ATP as substrate after 30 min by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488814(CHEMBL2295942)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of Homo sapiens (human) recombinant GST-tagged DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ and [gamma33P]ATP as substrate af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

LigandPNGBDBM50488814(CHEMBL2295942)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 and [gamma33P]ATP as substrate after 30 min by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article