BDBM50490986 CHEMBL2376674

SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1OCC[C@@H](O)Cn1cccn1

InChI Key InChIKey=NJFGDINHYKXYPM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490986   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Bayer Healthcare

Curated by ChEMBL

LigandBDBM50490986(CHEMBL2376674)Copy SMILESCopy InChI

Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL