BDBM50491679 CHEMBL2387430::US11419874, Example 3

SMILES COc1ccc(cc1-c1cnc(OC)nc1)C1=Nc2c(nn(CCO)c2C(=O)NC1)C(C)(C)C

InChI Key InChIKey=DCQBHFJFGDDQBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50491679   

LigandPNGBDBM50491679(CHEMBL2387430 | US11419874, Example 3)
Affinity DataIC50: 562nMAssay Description:Inhibition of PDE4B catalytic domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50491679(CHEMBL2387430 | US11419874, Example 3)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of PDE2 catalytic domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
LigandPNGBDBM50491679(CHEMBL2387430 | US11419874, Example 3)
Affinity DataIC50: 3.30nMAssay Description:Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2022
Entry Details
Go to US Patent