BDBM50492036 CHEMBL2391056

SMILES Cc1c(cc(-c2ccc(cc2)S(C)(=O)=O)n1-c1ccccc1)C#N

InChI Key InChIKey=SNUBEPJZUOUKOX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492036   

TargetProstaglandin G/H synthase 2(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50492036(CHEMBL2391056)
Affinity DataIC50: 360nMAssay Description:Inhibition of COX2 in mouse J774 cells assessed as inhibition of LPS-induced PGE2 production by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50492036(CHEMBL2391056)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX1 in mouse J774 cells using arachidonic acid as substrate assessed as inhibition of PGE2 production incubated for 15 mins prior to s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed