BDBM50492482 CHEMBL2402932

SMILES CC(C)C[C@@H]1NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)[C@@H](CCCN\C(N)=N/CCC[C@H](NC1=O)C(N)=O)NC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI Key InChIKey=IROFCLBXPGPSGK-UHFFFAOYSA-N

Data  3 KI  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50492482   

TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataIC50: 25nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataIC50: 145nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataKi: >500nMAssay Description:Displacement of [3H]-U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataEC50:  3.01E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492482(CHEMBL2402932)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed