BDBM50492490 CHEMBL2402936

SMILES N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]1CNC(=S)NC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC1=O)C(N)=O

InChI Key InChIKey=MNTOUKHSDQFMMF-UHFFFAOYSA-N

Data  5 KI  6 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50492490   

TargetMu-type opioid receptor(Guinea pig)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 1.80nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 2.40nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 36.3nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]-U69,593 from kappa opioid receptor in guinea pig brain membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataEC50:  250nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataEC50:  251nMAssay Description:Agonist activity at mu opioid receptor in rat brain membranes assessed as stimulation of [35S]GTPgammaS binding after 60 mins in presence of GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 416nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50492490(CHEMBL2402936)
Affinity DataIC50: 417nMAssay Description:Displacement of [3H]-DIDI from delta opioid receptor in Wistar rat brain membranes after 45 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed