BDBM50492591 CHEMBL2408083

SMILES Cc1cc(C)nc(NS(=O)(=O)c2ccc(cc2)\N=C\c2c(Cl)c3cc(cc(c3oc2=O)C(C)(C)C)C(C)(C)C)n1

InChI Key InChIKey=IPJOAGWGBYXHTH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492591   

TargetCarbonic anhydrase 9(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492591(CHEMBL2408083)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492591(CHEMBL2408083)
Affinity DataIC50: 173nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed