BDBM50492597 CHEMBL2408081

SMILES CC(C)(C)c1cc(c2oc(=O)c(\C=N\c3ccc(cc3)S(=O)(=O)Nc3nccs3)c(Cl)c2c1)C(C)(C)C

InChI Key InChIKey=DMRCDKYIGXAEKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492597   

TargetCarbonic anhydrase 2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492597(CHEMBL2408081)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492597(CHEMBL2408081)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed