BDBM50492601 CHEMBL2408089

SMILES Cc1ccc2oc(=O)c(\C=N\c3ccc(cc3)S(=O)(=O)Nc3nc(C)cc(C)n3)c(Cl)c2c1

InChI Key InChIKey=NPYBQILBEYWIFH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492601   

TargetCarbonic anhydrase 2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492601(CHEMBL2408089)
Affinity DataIC50: 141nMAssay Description:Inhibition of human recombinant CA2 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50492601(CHEMBL2408089)
Affinity DataIC50: 67nMAssay Description:Inhibition of human recombinant CA9 using 4-nitrophenylacetate as substrate preincubated for 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed