BDBM50493760 CHEMBL3436356

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CN4CCNCC4)o3)cc2Cl)c1

InChI Key InChIKey=XVMMZTTYUZMATQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493760   

TargetEpidermal growth factor receptor(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493760(CHEMBL3436356)
Affinity DataIC50: 11nMAssay Description:Inhibition of EGFR (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493760(CHEMBL3436356)
Affinity DataIC50: 12nMAssay Description:Inhibition of HER-2 (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed