BDBM50493762 CHEMBL3436358

SMILES CS(=O)(=O)N1CCN(Cc2ccc(o2)-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)CC1

InChI Key InChIKey=CQCHWVJIDPPZIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493762   

TargetEpidermal growth factor receptor(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493762(CHEMBL3436358)
Affinity DataIC50: 60nMAssay Description:Inhibition of EGFR (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493762(CHEMBL3436358)
Affinity DataIC50: 20nMAssay Description:Inhibition of HER-2 (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed