BDBM50493764 CHEMBL3436354

SMILES Fc1cccc(COc2ccc(Nc3ncnc4ccc(cc34)-c3ccc(CN4CCOCC4)o3)cc2Cl)c1

InChI Key InChIKey=KYIOPHOSYULFRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493764   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493764(CHEMBL3436354)
Affinity DataIC50: 13nMAssay Description:Inhibition of HER-2 (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Qilu Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50493764(CHEMBL3436354)
Affinity DataIC50: 26nMAssay Description:Inhibition of EGFR (unknown origin) using poly-(Glu4-Tyr) as substrate after 1 hr by ELISA-based spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed