BDBM50493837 CHEMBL2443298

SMILES Clc1ccc(CCNc2nc3n(-c4ccccc4)c(=S)n(-c4ccccc4)c(=S)c3c(=N)n2-c2ccccc2)cc1

InChI Key InChIKey=GWJXNWMIQJENFT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50493837   

TargetDNA topoisomerase 2-alpha(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50493837(CHEMBL2443298)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50493837(CHEMBL2443298)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human topoisomerase 2alpha-mediated relaxation of supercoiled pBR322 after 1 hr by ethidium bromide stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed