BDBM50493968 CHEMBL2442485

SMILES COc1ccc(cc1)-c1cc(nn1-c1nc(cs1)C(O)=O)C(F)(F)F

InChI Key InChIKey=WSWQLECWQBCTGC-UHFFFAOYSA-N

Data  4 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50493968   

TargetProstaglandin E2 receptor EP1 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human EP1 receptor by reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataKi: >2.70E+3nMAssay Description:Binding affinity to human EP4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at EP4 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at EP3 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataKi: >5.00E+3nMAssay Description:Binding affinity to human EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human EP1 receptor by intracellular Ca2+ release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataKi: >8.00E+3nMAssay Description:Binding affinity to human EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataIC50: 8.00E+3nMAssay Description:Antagonist activity at EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50493968(CHEMBL2442485)
Affinity DataKi:  8.70E+3nMAssay Description:Binding affinity to human EP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed