BDBM50494211 CHEMBL3087197

SMILES C=CC(=O)N1CC[C@@H](C1)N1C(=O)N(Cc2cnc(Nc3ccccc3)nc12)c1ccccc1

InChI Key InChIKey=JKMKVANXOAOXAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494211   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494211(CHEMBL3087197)
Affinity DataIC50: 235nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) after 1.5 hrs by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed