BDBM50494220 CHEMBL3087198

SMILES COc1cc(ccc1Nc1ncc2CN(C(=O)N([C@H]3CCN(C3)C(=O)C=C)c2n1)c1ccccc1)N1CCN(C)CC1

InChI Key InChIKey=ZIETVRSYZYJSDW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494220   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494220(CHEMBL3087198)
Affinity DataIC50: 15nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) after 1.5 hrs by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed