BDBM50494221 CHEMBL3087202

SMILES COc1cc(ccc1Nc1ncc2CN(C)C(=O)N([C@H]3CCN(C3)C(=O)C=C)c2n1)N1CCN(C)CC1

InChI Key InChIKey=WPKFTRYAFVFPIH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50494221   

TargetEpidermal growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50494221(CHEMBL3087202)
Affinity DataIC50: 525nMAssay Description:Inhibition of EGFR L858R/T790M double mutant (unknown origin) after 1.5 hrs by FRET-based Z'-Lyte assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed