BDBM50494333 CHEMBL3087677

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)NCCCNCCCNC3=CC(=O)C(NCCCNCCCNC(=O)Cc4c(C)n(C(=O)c5ccc(Cl)cc5)c5ccc(OC)cc45)=CC3=O)c2c1

InChI Key InChIKey=JHUOXQBVHUYPEY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50494333   

TargetCholinesterase(Human)
Alma Mater Studiorum University of Bologna

Curated by ChEMBL
LigandPNGBDBM50494333(CHEMBL3087677)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of human recombinant BuChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Alma Mater Studiorum University of Bologna

Curated by ChEMBL
LigandPNGBDBM50494333(CHEMBL3087677)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Alma Mater Studiorum University of Bologna

Curated by ChEMBL
LigandPNGBDBM50494333(CHEMBL3087677)
Affinity DataIC50: 6.11E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) aggregation (unknown origin) by thioflavin T fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed