BDBM50494512 CHEMBL3092906

SMILES CCN1CCN(CC1)c1nc(C)nc2[nH]c(nc12)-c1ccccc1Cl

InChI Key InChIKey=BWTWHSMZCKTAOD-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50494512   

TargetCannabinoid receptor 2(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494512(CHEMBL3092906)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]-CP-55940 from rat CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494512(CHEMBL3092906)
Affinity DataEC50:  4.70nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma binding after 30 mins by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494512(CHEMBL3092906)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494512(CHEMBL3092906)
Affinity DataEC50:  1.43E+3nMAssay Description:Agonist activity at human CB1 receptor expressed in Sf9 cells assessed as stimulation of [35S]GTPgamma binding incubated for 15 mins prior to [35S]GT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed