BDBM50494514 CHEMBL3092892

SMILES COCCn1c(nc2c(nc(C)nc12)N1CCN(CC1)C(C)=O)-c1ccccc1Cl

InChI Key InChIKey=ROMUYHFWPPWGLC-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50494514   

TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494514(CHEMBL3092892)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human CB2 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgamma binding after 30 mins by scintillation proximi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494514(CHEMBL3092892)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]-CP-55940 from human CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494514(CHEMBL3092892)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]-CP-55940 from rat CB2 receptor expressed in CHO cells after 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Lilly Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50494514(CHEMBL3092892)
Affinity DataEC50:  512nMAssay Description:Inverse agonist activity at human CB1 receptor expressed in Sf9 cells assessed as stimulation of [35S]GTPgamma binding incubated for 15 mins prior to...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed