BDBM50495042 CHEMBL3100125

SMILES Oc1cc(OCCCn2cc(\C=C3/C(=O)Nc4ccccc34)c3ccccc23)cc2oc(cc(=O)c12)-c1ccccc1

InChI Key InChIKey=KUHYCYZPVRQIEP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495042   

TargetProstaglandin G/H synthase 1(Sheep)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50495042(CHEMBL3100125)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50495042(CHEMBL3100125)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed