BDBM50495743 CHEMBL3113736

SMILES FC(F)Oc1ccc(cc1OCC1CC1)C(=O)O\C(=C/c1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1

InChI Key InChIKey=ULFAYKSQGUIMBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50495743   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50495743(CHEMBL3113736)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of PDE4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sichuan Academy of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50495743(CHEMBL3113736)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of PDE4 isolated from human U937 cells assessed as reduction in cAMP level by LANCE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed