BDBM50495900 CHEMBL3115263

SMILES Cn1cncc1[C@](C)(O)C1=Cc2cccnc2[C@@H](N2CCN(CC2)C(=O)Nc2ccc(cc2)C#N)c2ccc(Cl)cc12

InChI Key InChIKey=DJZAMXRHXDPZOJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495900   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50495900(CHEMBL3115263)Copy SMILESCopy InChI

Affinity DataIC50: 1.80nMAssay Description:Inhibition of FTase (unknown origin) assessed as transfer of [H3]farnesyl from [H3]farnesyl pyrophosphate to trichloroacetic acid-precipitable HaRas-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
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