BDBM50495905 CHEMBL3115426

SMILES CC(C)OC(=O)N1CCN(CC1)[C@H]1c2ccc(Cl)cc2C(=Cc2cccnc12)[C@@](C)(O)c1cncn1C

InChI Key InChIKey=YYDYJITZGLMMFM-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495905   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50495905(CHEMBL3115426)Copy SMILESCopy InChI

Affinity DataIC50: 0.600nMAssay Description:Inhibition of FTase (unknown origin) assessed as transfer of [H3]farnesyl from [H3]farnesyl pyrophosphate to trichloroacetic acid-precipitable HaRas-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
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