BDBM50495909 CHEMBL3115248

SMILES [H][C@]12C[C@]1(c1cc(Cl)ccc1[C@H](N1CCN(CC1)C(=O)OC(C)(C)C)c1ncccc21)C(C)(O)c1cncn1C

InChI Key InChIKey=JINSQACWIAVMPU-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50495909   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Merck Research Laboratories

Curated by ChEMBL

LigandBDBM50495909(CHEMBL3115248)Copy SMILESCopy InChI

Affinity DataIC50: 1.90nMAssay Description:Inhibition of FTase (unknown origin) assessed as transfer of [H3]farnesyl from [H3]farnesyl pyrophosphate to trichloroacetic acid-precipitable HaRas-...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
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