BDBM50495952 CHEMBL3121489

SMILES O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@@H](n2ccc(=O)[nH]c2=O)[C@@]11CCO1

InChI Key InChIKey=PUKAMKAIIRXNEI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50495952   

TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50495952(CHEMBL3121489)
Affinity DataKi:  130nMAssay Description:Inhibition of HCV RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepatitis C virus genotype 1b (isolate Con1) (HCV))
Janssen Infectious Diseases - Diagnostics

Curated by ChEMBL
LigandPNGBDBM50495952(CHEMBL3121489)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HCV RNA polymeraseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRNA-directed RNA polymerase(Hepacivirus C)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50495952(CHEMBL3121489)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of HCV genotype 1b recombinant NS5B RNA dependent RNA polymerase S282T mutant using IRES RNA as substrate after 30 mins by radioactive ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed