BDBM50496559 CHEMBL3127308

SMILES COc1c(-c2cc(nn2-c2ccc(cc2)S(N)(=O)=O)-c2cccnc2)c(O)cc2occc12

InChI Key InChIKey=KVOJQLZIQWXIOO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496559   

TargetProstaglandin G/H synthase 1(Sheep)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50496559(CHEMBL3127308)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ovine COX1 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by enzyme immuno...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50496559(CHEMBL3127308)
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant COX2 using arachidonic acid as substrate incubated for 10 mins prior to substrate addition measured after 2 mins by e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed