BDBM50496835 CHEMBL3218389

SMILES Cc1ccccc1S(=O)(=O)N1[C@@H](C[C@H]([C@@H]1c1ccc(Cl)cc1)C(O)=O)C(C)(C)C

InChI Key InChIKey=MWHMRNQLNHVBSC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50496835   

TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
University of Minnesota

Curated by ChEMBL

LigandBDBM50496835(CHEMBL3218389)Copy SMILESCopy InChI

Affinity DataIC50: 466nMAssay Description:Inhibition of human GGTase1 in human Burkitt lymphoma (Daudi) cell supernatant using [3H]geranylgeranylMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
Copy BDB DOIPubMed
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TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
University of Minnesota

Curated by ChEMBL

LigandBDBM50496835(CHEMBL3218389)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human recombinant FTase using [3H]farnesyldiphosphateMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
9/2/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL