BDBM50497267 CHEMBL3347501

SMILES [H][C@@]12CC(C)(C)[C@@]([H])([C@H](CC(C)=C)N1)c1ccccc21

InChI Key InChIKey=ZVZCYSQBQLWXCC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50497267   

TargetNADPH oxidase 5(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497267(CHEMBL3347501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX5 transfected in HEK cells assessed as inhibition of ionomycin-stimulated ROS generation by chemiluminescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCytochrome b-245 heavy chain(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497267(CHEMBL3347501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetNADPH oxidase 1(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497267(CHEMBL3347501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX1 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetCytochrome b-245 heavy chain(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50497267(CHEMBL3347501)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length human NOX2 transfected in COS 22 cells assessed as inhibition of Phorbol 12-myristate 13-acetate-stimulated ROS generation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed