BDBM50497439 CHEMBL3343700

SMILES Fc1cccc2cnn(\[#7]=[#6]-3\[#7]-[#6]-[#6]-[#7]-3)c12

InChI Key InChIKey=NREVCQNJBZJFTB-UHFFFAOYSA-N

Data  5 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50497439   

TargetNischarin(Rat)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataIC50: 7.74E+3nMAssay Description:Displacement of [3H]2BF1 from imidazoline I1 receptor in Sprague-Dawley rat kidney membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human alpha2A adrenoceptor expressed in CHO-K1 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]RX821002 from alpha2-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataKi:  65nMAssay Description:Displacement of [3H]RS-79948-197 from human alpha2A adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-2B adrenergic receptor(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]RS-79948-197 from human alpha2B adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-2C adrenergic receptor(Human)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]RS-79948-197 from human alpha2C adrenoceptor expressed in CHO-K1 cells after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Medical University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50497439(CHEMBL3343700)
Affinity DataKi:  1.63E+3nMAssay Description:Displacement of [3H]prazosin from alpha1-adrenoceptor in Sprague-Dawley rat brain membranes after 45 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed