BDBM50497791 CHEMBL3330118

SMILES CNc1nccc(n1)-c1cc(C(N)=O)c([nH]1)-c1cc(Cl)ccc1C

InChI Key InChIKey=BGPKIRZIIRONDF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50497791   

TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497791(CHEMBL3330118)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497791(CHEMBL3330118)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of JAK2 V617F mutant in human SET2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed