BDBM50497797 CHEMBL3330120

SMILES CN1CCN(CC1)c1ccc(Nc2nccc(n2)-c2cc(C(N)=O)c([nH]2)-c2cc(Cl)ccc2C)cc1

InChI Key InChIKey=RZBOHPWHBKCYMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50497797   

TargetTyrosine-protein kinase JAK2(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50497797(CHEMBL3330120)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant human JAK2 (808-1132 residues) using LPLDKDYYVVREPGQ as substrate by radiometric assay in presence of [33P]-gamma-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed