BDBM50497837 CHEMBL3323283

SMILES [H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O)OC(=O)[C@H](CO)c1ccccc1

InChI Key InChIKey=IZPDHAHWQOHFNJ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50497837   

TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  6.90nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 W422A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  7.10nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y177Q/T423H mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  8.10nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M2 receptor expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M5(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
University of W£Rzburg

Curated by ChEMBL
LigandPNGBDBM50497837(CHEMBL3323283)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-NMS from human muscarinic M2 Y104A mutant expressed in Flp-In-CHO cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed