BDBM50498876 CHEMBL3634634

SMILES CC1(C)N=C(N)N=C(N)N1c1ccc(CN)cc1

InChI Key InChIKey=AFRWRNQNACDMJY-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498876   

TargetDihydrofolate reductase(Escherichia coli)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50498876(CHEMBL3634634)
Affinity DataKd:  1.45E+5nMAssay Description:Binding affinity to Escherichia coli DHFR at 500 uM using spyro orange reporter dye by differential scanning fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50498876(CHEMBL3634634)
Affinity DataIC50: 7.22E+5nMAssay Description:Inhibition of Escherichia coli DHFR assessed as NADP formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50498876(CHEMBL3634634)
Affinity DataKi:  3.93E+4nMAssay Description:Inhibition of Escherichia coli DHFR assessed as NADP formation by quadratic Morrison plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed