BDBM50498890 CHEMBL3735924::US10744117, Compound IB-2

SMILES C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=WKDKAVKAQXVFJV-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50498890   

TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50498890(CHEMBL3735924 | US10744117, Compound IB-2)
Affinity DataIC50: 5nMAssay Description:Binding affinity to GST-tagged PPAR-gamma-LBD (unknown origin) after 2 hrs by Lantha screen assay using fluormone Pan-PPAR green probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50498890(CHEMBL3735924 | US10744117, Compound IB-2)
Affinity DataEC50:  355nMAssay Description:Transactivation of human PPARgamma in HEK293T cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50498890(CHEMBL3735924 | US10744117, Compound IB-2)
Affinity DataIC50: 3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2021
Entry Details
US Patent