BDBM50499148 CHEMBL3734983

SMILES CN1CCN(CC1)c1ccc2nc(c(-c3ccncc3)n2n1)-c1ccc2ncsc2c1

InChI Key InChIKey=SSGUNNUGCYUWCP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50499148   

TargetCyclin-dependent kinase 5 activator 1(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499148(CHEMBL3734983)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 expressed in Escherichia coli using histone H1 substrate after 30 mins by scintillation and luminescence cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499148(CHEMBL3734983)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant haspin kinase domain expressed in Escherichia coli BL21-KRX using histone H3 (1 to 21) peptide substrate after 30 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499148(CHEMBL3734983)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human GST-tagged RIPK3 expressed in Spodoptera frugiperda Sf9 cells after 30 mins by scintillation and luminescence countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University of Tours

Curated by ChEMBL
LigandPNGBDBM50499148(CHEMBL3734983)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of porcine brain GSK-3 alpha/beta using GS-1 substrate after 30 mins by scintillation and luminescence counting method in the presence of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed