BDBM50499900 CHEMBL3740183

SMILES CCCCNC(=O)c1ccn2c(NCc3ccc(NC(N)=N)cc3)cnc2c1

InChI Key InChIKey=BEACCZKINFJRSI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50499900   

TargetCoagulation factor X(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of purified human factor 10a using Suc-Ile-Glu(gammaPip)-GlyArg-pNa-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma thrombin using pyroGlu-Pro-Arg-pNA-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPlasma kallikrein(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma kallikrein using D-Pro-Phe-Arg-pNA-2HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant human tPA using H-D-Ile-Pro-L-Arg-pNA-2HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of purified human factor 7a using MeSO2-Cha-Abu-Arg-pNA as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 97nMAssay Description:Inhibition of human uPA using pyro-Glu-Gly-Arg-pNA as substrate assessed as para-nitroaniline release from substrate measured for 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetPlasminogen(Human)
University of Antwerp (Ua)

Curated by ChEMBL
LigandPNGBDBM50499900(CHEMBL3740183)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human plasma plasmin using pyroGlu-Pro-Arg-pNA-HCl as substrate measured for 5 mins by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed