BDBM50500165 CHEMBL3746526

SMILES CCCOc1ccc(cc1NS(=O)(=O)\C=C\c1ccccc1)C(=O)OCCN(CC)CC

InChI Key InChIKey=JRVDSTNSNFIQIE-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50500165   

TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)
Affinity DataKd:  5.53E+4nMAssay Description:Binding affinity to human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) by tryptophan fluorescence quenching assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetRibonucleoside-diphosphate reductase large subunit(Human)
Case Western Reserve University

Curated by ChEMBL
LigandPNGBDBM50500165(CHEMBL3746526)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human ribonucleotide reductase M1 subunit expressed in Escherichia coli BL21 (DE3) using 14C-ADP as substrate by liquid scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed