BDBM50500957 CHEMBL3798039

SMILES F[C@H]1CCN(C1)C(=O)CN1CCN(CC1=O)c1cccc2n(ncc12)-c1ccccc1F

InChI Key InChIKey=SYLLWFIHDZDGIO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50500957   

LigandPNGBDBM50500957(CHEMBL3798039)
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500957(CHEMBL3798039)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell-patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500957(CHEMBL3798039)
Affinity DataIC50: 540nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed