BDBM50500958 CHEMBL3798320

SMILES [H][C@@]12CN(C[C@]1([H])C(=O)N(C2)c1cccc2n(ncc12)-c1ccccc1F)C(=O)CC(C)(C)O

InChI Key InChIKey=RLXGMHWKXRLKHB-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50500958   

LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human Nav1.3 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 340nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293F cells measured at -65 mV holding potential by voltage-patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human Nav1.6 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK293 cells by whole cell-patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant human Nav1.7 expressed in HEK293F cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
LigandPNGBDBM50500958(CHEMBL3798320)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human Nav1.2 expressed in HEK293 cells preincubated for 40 mins followed by DiSBAC2 substrate addition measured after 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed