BDBM50501582 CHEMBL4098475

SMILES CCN1CCN(CC1)c1ccc(Nc2ncc(F)c(n2)-c2sc(NC3CCCC3)nc2C)nc1

InChI Key InChIKey=UVEBMCRIHHZDFG-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50501582   

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50501582(CHEMBL4098475)
Affinity DataKi:  2nMAssay Description:Inhibition of CDK4/cyclin D1 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D3(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50501582(CHEMBL4098475)
Affinity DataKi:  6nMAssay Description:Inhibition of CDK6/cyclin D3 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50501582(CHEMBL4098475)
Affinity DataKi:  349nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50501582(CHEMBL4098475)
Affinity DataKi:  685nMAssay Description:Inhibition of CDK7/cyclin H (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University of South Australia

Curated by ChEMBL
LigandPNGBDBM50501582(CHEMBL4098475)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) in presence of [gamma-33P]-ATP by KINOMEscan assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2020
Entry Details Article
PubMed